The scientists are the UK has found a way to make variants of breast cancer drug pill effective against other types of cancers. A "miracle cures" for breast cancer disease is rumored to be a universal weapon against tumors.
According to the scientists are at the University of Newcastle (Monday, June 27, 2011), the findings led to a new drug that absorbs more or even all in all tumor types and side effects such as nausea and less fatigue. Central stimulation in the family of cancer medicines known as PARP barrier growth, which affect the way tumor cells repair themselves. This drug is targeting a derivative form of breast cancer, which applies also to the prostate gland cancer and pancreatic tumors with the same harmful genes. The drug is a special interest of physicians because they are out to eradicate the tumor and kill it without harming healthy cells.
So this means that the patients suffered fewer side effects than they do chemotherapy or radiotherapy, in which healthy cells unaffected.
And the drug was digging "Achilles' heel of a derivative form of breast cancer. This was caused by a defect in a gene called BRCA1, which limits the ability of cells to repair their DNA.
For the health of the cell has two ways of facing the damage 'that enable breed, grow and spread', but cells in BRCA tumors have only one fruit. PARP inhibits the growth of the remaining barriers that path, stopping the tumor cells to multiply, eventually drove him to death. Some tumors of the breast, cervix and prostate were destroyed in a matter of BRCA genes but a small proportion of all cancers.
From the research that will allow the drug to be used in tumors that do not have this genetic damage, which effectively "reinvent" the damage. Experiments conducted on mice who develop lung tumors, the researchers showed ambush of a molecule called Cdk1 also stop DNA repair. And when the animal is given a growth barrier PARP, It successfully eradicate cancer, according to the journal Nature medicine.
According to the researchers, Professor Nicola Curtin, blocking Cdk1 assist DNA repair in cancer cells, making them sensitive to PARP growth barrier. The researchers were able to show that this approach targeting only cancer cells. Now they need to develop an effective drug that can block Cdk1, so that many patients can be helped from treatment with PARP growth barrier. It is widely applicable, chances are universal. And in fact has more, that damages the cells that make vulnerable to PARP inhibitors can be re-created growth in lung cancer is very possible. It is still very early, but it is quite interesting.
Meanwhile, according to Dr Lesley Walker, of Cancer Research UK, which funded the research, that they now have a powerful new tool for treating cancer patients
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